Pepperoni-Stuffed Bread: Cheesy, Savory Pull-Apart Loaf

Stuffed Pepperoni Bread combines pepperoni, mozzarella, and Italian seasoning wrapped in refrigerated bread dough, baked until golden and gooey, and served with warm marinara for dipping.

We love all things Italian-inspired, and this stuffed pepperoni bread delivers those familiar pizza flavors in a simple, crowd-pleasing package. It works well as an appetizer or an easy weeknight main.

❤️ Why You’ll Love This Recipe

• Made with a handful of simple, easy-to-find ingredients.
• Quick prep — ready in minutes, plus a short bake time.
• All the familiar pepperoni pizza flavors in a portable, shareable loaf.
• Using frozen bread dough keeps the process fast and foolproof.

🛒Ingredients

This recipe uses just six main ingredients you can pick up in one trip to the grocery store. Check the recipe card below for exact amounts.

• Frozen bread dough (thawed)
• Deli-sliced pepperoni
• Sliced mozzarella cheese
• Egg (for egg wash)
• Italian seasoning
• Marinara sauce for dipping

🔪 How to Make Stuffed Pepperoni Bread

Prep takes only a few minutes, then bake for about 30–35 minutes until the loaf is golden and cooked through.

Step 1: Prep

Preheat the oven to 350°F (175°C). Line a baking sheet with parchment paper and set aside.

Step 2: Layer

Roll the dough into a roughly 12×10-inch rectangle. Arrange a single layer of pepperoni evenly across the dough, then top with the sliced mozzarella.

Step 3: Roll

Starting from the longer side, roll the dough into a tight log. Transfer the roll to the prepared baking sheet.

Step 4: Bake

Beat the egg and brush it over the roll. Sprinkle with Italian seasoning, then bake 30–35 minutes, until the crust is golden and the filling is hot.

Step 5: Cool and Slice

Let the loaf rest 10–15 minutes so the cheese firms slightly, then slice and serve with warm marinara for dipping.

📝Variations

Customize this recipe to suit your tastes with a few simple swaps or additions.

• Spicy – Add red pepper flakes over the cheese before rolling.
• Extra cheesy – Sprinkle shredded mozzarella or Parmesan on top before baking.
• Alternative fillings – Use cooked ground beef, Italian sausage, bacon, or Canadian bacon in place of or in addition to pepperoni (cook meats first).
• Additional toppings – Try sliced olives, onions, bell peppers, mushrooms, or your favorite pizza toppings, but don’t overfill or it will be hard to roll.

🥄 Equipment

• Measuring spoon
• Mixing bowl
• Baking sheet
• Parchment paper

🥫 Storage

Store leftovers in an airtight container in the refrigerator for up to 3 days. For longer storage, wrap the cooled loaf tightly in plastic wrap and foil, then freeze up to 2 months. Reheat slices in a 350°F oven until warmed through.

💭 Tips

• Use a single layer of pepperoni and cheese to avoid over-stuffing and leaking while baking.
• If using ground or cured meats other than pepperoni, cook them fully before assembling.
• Line the baking sheet with parchment for easy cleanup and to prevent sticking.
• Keep additional toppings light so the dough remains easy to roll.

⁉️ FAQ

Here are answers to common questions about pepperoni bread.

🍽 More Pepperoni Recipes

If you enjoy pepperoni, try other easy recipes that highlight the flavor.

• Pepperoni Pasta Salad
• Pepperoni Pizza Pinwheels
• Puff Pastry Pizza Bites

📌 PIN IT!!

🧾Recipe Card

Print or save this recipe card so you can make the loaf again.